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Frustrated with their party's response to President Trump, a wave of young Democrats are challenging incumbents in safe blue districts, hoping to mirror Alexandria Ocasio-Cortez's upset win in 2018.

Pope Francis' body lies in state for public viewing at St. Peter's Basilica as the Vatican prepares for his funeral on Saturday.

NPR's Steve Inskeep speaks with former Deputy Assistant Secretary of Defense Evelyn Farkas about Defense Secretary Pete Hegseth's use of private Signal chats and the turmoil inside the Pentagon.

Gregory Cheadle tells NPR he was not offended when presumptive GOP nominee Donald Trump pointed to him at a recent California campaign rally and said, "Look at my African-American over here."

The world has wiped out only one human disease: smallpox. Guinea worm disease looks like it's on the verge of being the second.

Experts believe the self-deportation offer will only appeal to a small portion of migrants already considering return, but unlikely to spur high demand.

Another round of dangerous weather is forecast to reach areas in the Southeast on Tuesday, as recovery efforts continued following a deadly bout of severe weather that affected multiple states.

At a campaign event, Donald Trump said Bob Guillo gave his Trump University program the highest rating possible. Guillo says he paid $35,000 only to be taught to use Trulia and other common websites.

A major medical group now recommends pain-blocking treatments for IUD insertion and other procedures amid a growing recognition that women's pain should be treated.

New books out this week look at everything from pressing political concerns — Original Sin — to perspective-altering riddles about life itself, like in Is A River Alive? and The Book of Records.