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After decades of devastating increases driven by fentanyl and other toxic street drugs, overdose deaths are dropping sharply in much of the U.S. The trend could mean roughly 20,000 fewer deaths in 2024.

Hundreds of costumed "Helens" are cheerfully invading bars across the country in honor of Helen Roper, from the 1970s sitcom Three's Company.

Talking to historian and author Robert Caro is like stepping into a time machine, as NPR discovered on a visit to his New York office recently.

The number of people coming into the U.S. from Canada continues to increase. We visit border communities in New York, where the response to migrants is mixed.

NPR's Michel Martin talks to former Democratic National Committee chair Howard Dean about Democrats' response to President Biden's debate performance, and whether Biden should drop out of the race.

Homeland Security Secretary Alejandro Mayorkas says recent policies secure the border and make immigration rules more fair to people already in the country.

Michigan is a pivotal state in 2024 — and one that the Biden campaign sees as part of its path to victory. But Democrats are still weighing how to move forward after Biden's recent stumbles.

The decision likely ensures that the case against Trump won't be tried before the election, and then only if he is not reelected.

The Minnesota governor speaks at the DNC in Chicago on Wednesday. Walz has gone from a relatively unknown politician to accepting the Democratic nomination for vice president in two short weeks.

Early in life, the protein Reelin helps assemble the brain. Later on, it appears to protect the organ from Alzheimer's and other threats to memory and thinking.